Description

3-Hydroxy-2-(2,2,2-Trimethylacetamido)Pyridine is a specialized pyridine derivative characterized by a hydroxy group and a trimethylacetamido (pivalamido) substituent. This compound serves as a crucial advanced pharmaceutical intermediate (API intermediate) and a versatile building block in organic synthesis. It is primarily required by pharmaceutical R&D and fine chemical synthesis sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Chemical Synthesis: Used as a precursor for creating more complex heterocyclic compounds and functionalized pyridines.
• Research & Development: Valuable reagent in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Intermediates: Potential use in the synthesis of advanced crop protection agents.
• Ligand Synthesis: Can be utilized in the preparation of specialized ligands for catalysis or metal complexation.

Basic Information

Product Name	3-Hydroxy-2-(2,2,2-Trimethylacetamido)Pyridine
CAS No.	177741-83-2
Molecular Formula	C10H14N2O2
Molecular Weight	194.23 g/mol
Synonyms	2-Pivalamido-3-hydroxypyridine; 3-Hydroxy-2-pivalamidopyridine; 2-(2,2,2-Trimethylacetamido)-3-hydroxypyridine; 3-Hydroxy-2-(trimethylacetamido)pyridine; 3-Hydroxy-2-pivaloylaminopyridine; 2-(Pivaloylamino)-3-pyridinol; 3-Pyridinol, 2-[(2,2-dimethyl-1-oxopropyl)amino]-; 177741-83-2
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-2-(2,2,2-Trimethylacetamido)Pyridine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.