Description

4-Methyl-3-Thiopheneboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound is a critical reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex thiophene-containing molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and advanced functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing thiophene-based drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the thiophene moiety imparts specific biological activity.
• Material Science & OLED Development: Serves as a precursor for synthesizing conjugated polymers and organic semiconductors used in light-emitting diodes (OLEDs) and electronic devices.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile building block for exploring new chemical space and creating complex molecular architectures in academic and industrial R&D settings.

Basic Information

Product Name	4-Methyl-3-Thiopheneboronic Acid
CAS No.	177735-11-4
Molecular Formula	C5H7BO2S
Molecular Weight	141.98 g/mol
Synonyms	(4-Methyl-3-thienyl)boronic acid; 3-Borono-4-methylthiophene; 4-Methylthiophene-3-boronic acid; 4-Methyl-3-thienylboronic acid; 3-Thiopheneboronic acid, 4-methyl-; 4-Methyl-3-thiophenylboronic acid; Boronic acid, B-(4-methyl-3-thienyl)-
EINECS	Contact for details

Quality Control

Every batch of 4-Methyl-3-Thiopheneboronic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.