Description

5-o-Adamantancarbonyl-2,3-o-Isopropylidene-D-Ribofuranose is a sophisticated, high-purity chemical intermediate featuring a protected ribofuranose scaffold coupled with an adamantane moiety. This compound is critical for its role in the synthesis of complex nucleoside analogs and other biologically active molecules, offering a unique combination of steric bulk and chemical stability. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral agents, modified oligonucleotides, and novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer research.
• Antiviral Drug Development: Used in the research and production of potential therapeutic agents targeting viruses such as hepatitis and influenza.
• Oligonucleotide Synthesis: Serves as a modified sugar precursor for creating specialized oligonucleotides with enhanced properties for diagnostics and therapeutics.
• Glycochemistry Research: Valuable intermediate in academic and industrial research focused on carbohydrate chemistry and glycoconjugate synthesis.
• Prodrug Synthesis: Employed in the design and development of prodrugs to improve the bioavailability and targeting of active pharmaceutical ingredients.
• Chemical Biology Probes: Used to create labeled or modified nucleosides for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	5-o-Adamantancarbonyl-2,3-o-Isopropylidene-D-Ribofuranose
CAS No.	177415-06-4
Molecular Formula	C19H28O6
Molecular Weight	352.42 g/mol
Synonyms	1-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]oxycarbonyladamantane; 5-O-(Adamantane-1-carbonyl)-2,3-O-isopropylidene-D-ribofuranose; 1-[(3aR,4R,6R,6aR)-2,2-Dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl]methoxycarbonyladamantane; Adamantane-1-carboxylic acid (2,3-O-isopropylidene-D-ribofuranos-5-yl) ester; Protected D-ribofuranose adamantoyl ester.
EINECS	Contact for details

Quality Control

Our 5-o-Adamantancarbonyl-2,3-o-Isopropylidene-D-Ribofuranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring material suitable for advanced research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be stored away from light. Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.