Description

tert-Butyl 4-[(2-Ethoxy-2-Oxoethyl)Amino]Tetrahydro-1(2H)-Pyridinecarboxylate is a high-purity, protected amino acid derivative and a key synthetic intermediate in advanced organic chemistry. This compound matters for its role as a crucial building block in the synthesis of complex molecules, offering a reactive amine group protected by a Boc (tert-butoxycarbonyl) group and an ethoxycarbonylmethyl side chain. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Peptidomimetic Synthesis: Used to introduce constrained, non-natural amino acid residues into peptide chains to enhance stability and biological activity.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic compounds and exploring new chemical spaces in academic and industrial R&D.
• Protecting Group Chemistry: The Boc-protected amine functionality allows for selective deprotection under mild acidic conditions, enabling sophisticated sequential synthesis strategies.
• Ligand and Catalyst Development: Potential use as a precursor for creating chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	tert-Butyl 4-[(2-Ethoxy-2-Oxoethyl)Amino]Tetrahydro-1(2H)-Pyridinecarboxylate
CAS No.	177276-49-2
Molecular Formula	C14H26N2O4
Molecular Weight	286.37 g/mol
Synonyms	1-Boc-4-[(Ethoxycarbonylmethyl)amino]piperidine; 4-[(2-Ethoxy-2-oxoethyl)amino]-1-(tert-butoxycarbonyl)piperidine; tert-Butyl 4-[(ethoxycarbonylmethyl)amino]piperidine-1-carboxylate; 1-N-Boc-4-[(carbethoxymethyl)amino]piperidine; 4-(N-Carbethoxymethyl)amino-1-N-Boc-piperidine; 1-(tert-Butoxycarbonyl)-4-[(ethoxycarbonylmethyl)amino]piperidine; Boc-4-[(Ethoxycarbonylmethyl)amino]piperidine; N-Boc-4-[(Ethoxycarbonylmethyl)amino]piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[(2-Ethoxy-2-Oxoethyl)Amino]Tetrahydro-1(2H)-Pyridinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent identity, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.