Description

Carbamic Acid, [(Trimethylsilyl)Methyl]-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organosilicon-protected carbamate derivative, serving as a valuable synthetic intermediate in advanced organic synthesis. Its core value lies in providing a protected amine functionality that is stable under a wide range of reaction conditions, enabling precise molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable building blocks for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those requiring the controlled introduction of amine groups.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where its protected carbamate group offers strategic synthetic advantages.
• Peptide Mimetics & PROTACs: Employed in the construction of peptide-like structures and proteolysis-targeting chimeras (PROTACs) for targeted protein degradation.
• Material Science Research: Serves as a precursor for functionalized silanes used in surface modification, polymer cross-linking, and the creation of hybrid organic-inorganic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	Carbamic Acid, [(Trimethylsilyl)Methyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	177176-90-8
Molecular Formula	C9H21NO2Si
Molecular Weight	203.35 g/mol
Synonyms	tert-Butyl [(trimethylsilyl)methyl]carbamate; N-[(Trimethylsilyl)methyl]carbamic Acid tert-Butyl Ester; (Trimethylsilylmethyl)carbamic Acid tert-Butyl Ester; BOC-NH-CH2-Si(CH3)3; N-(tert-Butoxycarbonyl)-1-(trimethylsilyl)methanamine; 1,1-Dimethylethyl N-[(Trimethylsilyl)methyl]carbamate; tert-Butyl (trimethylsilylmethyl)carbamate
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(Trimethylsilyl)Methyl]-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to reliable supply and traceability supports our customers' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.