Description

Cyclohexyl (4-Nitrophenyl) Carbonate (CAS NO 176787-42-1) is a specialized organic carbonate ester of significant interest in advanced synthetic chemistry. This compound serves as a versatile and reactive intermediate, enabling the controlled introduction of the cyclohexyloxycarbonyl protecting group or as an activated carbonate for derivatization. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and complex molecules where precise functional group manipulation is required.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for carbamate prodrugs and protecting group strategies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that utilize carbonate functionalities.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialized polycarbonates and polymeric materials with tailored properties.
• Organic Synthesis Reagent: Employed as an efficient reagent for the introduction of the cyclohexyloxycarbonyl (Choc) protecting group for amines and alcohols in multi-step syntheses.
• Chemical Biology Tool: Utilized in bioconjugation and probe development due to its reactivity with nucleophilic functional groups in biomolecules.
• Material Science: Investigated for creating advanced organic frameworks and surface modifications where its specific carbonate linkage is beneficial.

Basic Information

Product Name	Cyclohexyl (4-Nitrophenyl) Carbonate
CAS No.	176787-42-1
Molecular Formula	C₁₃H₁₅NO₅
Molecular Weight	265.26 g/mol
Synonyms	4-Nitrophenyl cyclohexyl carbonate; Cyclohexyl 4-nitrophenyl carbonate; p-Nitrophenyl cyclohexyl carbonate; Carbonochloridic acid, 4-nitrophenyl cyclohexyl ester; (4-Nitrophenyl) cyclohexyl carbonate; Cyclohexyloxycarbonyl 4-nitrophenyl ester; Choc-ONp; Cyclohexyl p-nitrophenyl carbonate
EINECS	Contact for details

Quality Control

Our Cyclohexyl (4-Nitrophenyl) Carbonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.