Description

2,5-Dichloronicotinaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of its reactive aldehyde and chlorine groups, enabling precise molecular construction for complex target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized to create tagged molecules and activity-based probes for studying enzymatic function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental substrate for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2,5-Dichloronicotinaldehyde
CAS No.	176433-49-1
Molecular Formula	C6H3Cl2NO
Molecular Weight	176.00 g/mol
Synonyms	2,5-Dichloro-3-pyridinecarboxaldehyde; 2,5-Dichloropyridine-3-carbaldehyde; 3-Pyridinecarboxaldehyde, 2,5-dichloro-; 2,5-Dichloro-3-formylpyridine; 2,5-Dichloronicotinaldehyde; Nicotinaldehyde, 2,5-dichloro-; 2,5-Dichloro-3-pyridylcarboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2,5-Dichloronicotinaldehyde is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.