Description

L-Valine, 3-Methyl-, Phenylmethyl Ester, Hydrochloride is a high-purity, protected amino acid derivative essential for advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block for the development of novel peptides and bioactive molecules, offering precise stereochemical control. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the creation of complex APIs and specialized intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected valine derivative, enabling the construction of complex peptide sequences.
• Biochemical Research: Employed in proteomics and metabolic pathway studies as a specialized reagent or standard.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective organic synthesis for creating enantiomerically pure compounds.
• Fine Chemical Production: Utilized in the manufacture of advanced agrochemicals, specialty polymers, and other high-value fine chemicals requiring specific stereochemistry.

Basic Information

Product Name	L-Valine, 3-Methyl-, Phenylmethyl Ester, Hydrochloride
CAS No.	176388-88-8
Molecular Formula	C14H21NO2 • HCl
Molecular Weight	271.78 g/mol
Synonyms	L-Valine, 3-methyl-, phenylmethyl ester, hydrochloride; Benzyl L-3-methylvalinate hydrochloride; (S)-Benzyl 3-methylvalinate hydrochloride; L-3-Methylvaline benzyl ester hydrochloride; N-Benzyloxycarbonyl-L-3-methylvaline; Boc-L-3-methylvaline benzyl ester (related protected form); Valine derivative, protected, hydrochloride salt; Chiral valine ester hydrochloride
EINECS	Contact for details

Quality Control

Our L-Valine, 3-Methyl-, Phenylmethyl Ester, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research and fine chemical synthesis. A Certificate of Analysis (COA) detailing identity, purity (typically >98%), and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.