Description

Spiro[Bicyclo[4.1.0]Heptane-7,1-Cyclopentan]-3-Ol, 2-Methyl-, [1-α-,6-α-,7-α-(2R*,3R*)]- (9Ci) is a complex, stereochemically defined spirocyclic alcohol of significant interest in advanced organic synthesis. This compound matters as a versatile and sophisticated chiral building block, enabling the construction of intricate molecular architectures with precise three-dimensional control. It is primarily needed by research chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, complex natural product analogs, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring complex polycyclic frameworks.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its unique spirocyclic structure can contribute to novel modes of action.
• Asymmetric Catalysis Ligand Precursor: The defined stereocenters and functional groups make it a candidate for developing novel chiral ligands or organocatalysts.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific stereoregularity and thermal properties.
• Natural Product & Fragrance Synthesis: Employed in the total synthesis of complex natural products or as a starting point for creating novel, high-value fragrance molecules.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, exploring new spiroannulation and stereoselective transformation reactions.

Basic Information

Item	Detail
Product Name	Spiro[Bicyclo[4.1.0]Heptane-7,1-Cyclopentan]-3-Ol, 2-Methyl-, [1-α-,6-α-,7-α-(2R*,3R*)]- (9Ci)
CAS No.	176299-06-2
Molecular Formula	C12H18O
Molecular Weight	178.27 g/mol
Synonyms	2-Methylspiro[bicyclo[4.1.0]heptane-7,1'-cyclopentan]-3-ol; (1R*,2R*,6S*,7R*)-2-Methylspiro[bicyclo[4.1.0]heptane-7,1'-cyclopentan]-3-ol; Spiro[bicyclo[4.1.0]heptane-7,1'-cyclopentan]-3-ol, 2-methyl-, (1α,2α,6β,7α)-; 176299-06-2; Spirocyclic alcohol derivative; Chiral spiro alcohol building block.
EINECS	Contact for details

Quality Control

Our Spiro[Bicyclo[4.1.0]Heptane-7,1-Cyclopentan]-3-Ol, 2-Methyl-, [1-α-,6-α-,7-α-(2R*,3R*)]- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, enantiomeric/excess, and stereochemical integrity. Standard testing includes chiral HPLC, NMR, and GC-MS. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider inert atmosphere conditions to maintain optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.