Description

4-[(S)-3-Amino-2-Oxopyrrolidin-1-Yl)Benzonitrile Hydrochloride is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. This compound is valued for its role as a key building block in the development of active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and scale-up of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex drug molecules, particularly protease inhibitors and other enzyme-targeted therapies.
• API Development: Used in research and development for constructing the core scaffold of new Active Pharmaceutical Ingredients (APIs).
• Preclinical & Clinical Research: Serves as a key material in the synthesis of compounds for pharmacological screening and early-stage clinical trial materials.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale manufacturing of advanced pharmaceuticals.
• Chemical Biology Probes: Can be utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	4-[(S)-3-Amino-2-Oxopyrrolidin-1-Yl)Benzonitrile Hydrochloride
CAS No.	175873-08-2
Molecular Formula	C11H12N4O·HCl
Molecular Weight	252.70 g/mol
Synonyms	(S)-4-(3-Amino-2-oxopyrrolidin-1-yl)benzonitrile hydrochloride; 1-(4-Cyanophenyl)-(S)-3-amino-2-pyrrolidinone hydrochloride; 4-[(3S)-3-Amino-2-oxo-1-pyrrolidinyl]benzonitrile hydrochloride; (S)-1-(4-Cyanophenyl)-3-aminopyrrolidin-2-one hydrochloride; 175873-08-2; UNII-6K1W8S6857; 6K1W8S6857
EINECS	Contact for details

Quality Control

Our 4-[(S)-3-Amino-2-Oxopyrrolidin-1-Yl)Benzonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP starting material applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.