Description

3-Bromo-n-Boc-L-Alanine Methyl Ester CAS NO 175844-11-8 is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the precise introduction of bromoalanine motifs into complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, proteomimetics, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptide-based drugs and bioactive molecules.
• Peptide Chemistry: Used for the site-specific incorporation of brominated alanine residues in solid-phase and solution-phase peptide synthesis (SPPS).
• Protease Inhibitor Development: Serves as a building block for creating inhibitors that target specific enzymatic pathways.
• Chemical Biology Probes: Enables the synthesis of labeled or modified peptides for studying protein-protein interactions and cellular processes.
• Agrochemical Research: Employed in the development of novel peptide-inspired crop protection agents.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research.

Basic Information

Product Name	3-Bromo-n-Boc-L-Alanine Methyl Ester
CAS No.	175844-11-8
Molecular Formula	C9H16BrNO4
Molecular Weight	282.13 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)amino]-3-bromopropanoic acid methyl ester; Methyl (2S)-3-bromo-2-[(tert-butoxycarbonyl)amino]propanoate; Boc-L-3-bromoalanine methyl ester; (S)-Methyl 3-bromo-2-((tert-butoxycarbonyl)amino)propanoate; N-Boc-3-bromo-L-alanine methyl ester; 3-Bromo-N-(tert-butoxycarbonyl)-L-alanine methyl ester; L-Alanine, 3-bromo-N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our 3-Bromo-n-Boc-L-Alanine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The compound is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.