Description

2H-Pyrrolo[3,4-C]Pyridine-2-Acetic Acid, 7-Amino-1,3-Dihydro--α-,6-Dimethyl-1,3-Dioxo- is a high-purity, heterocyclic organic compound with a complex fused ring structure, serving as a critical advanced pharmaceutical intermediate. Its value lies in enabling the synthesis of novel, potent active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on developing new central nervous system (CNS) and oncology drugs. CAS No. 175478-47-4.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for creating new APIs with pyrrolopyridine core structures.
• Biochemical Research: Serves as a crucial reagent in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis and scale-up projects for clients.
• Preclinical & Clinical Trial Material: Sourced for the production of materials required for non-clinical studies and early-phase clinical trials.
• Proteolysis Targeting Chimera (PROTAC) Development: Potential use as a component in the design of bifunctional molecules for targeted protein degradation.

Basic Information

Product Name	2H-Pyrrolo[3,4-C]Pyridine-2-Acetic Acid, 7-Amino-1,3-Dihydro--α-,6-Dimethyl-1,3-Dioxo-
CAS No.	175478-47-4
Molecular Formula	C12H13N3O4
Molecular Weight	263.25 g/mol
Synonyms	7-Amino-α,6-dimethyl-1,3-dihydro-2H-pyrrolo[3,4-c]pyridine-1,3-dione-2-acetic acid; 2-(7-Amino-α,6-dimethyl-1,3-dioxo-1,3-dihydro-2H-pyrrolo[3,4-c]pyridin-2-yl)acetic acid; 175478-47-4; Pyrrolo[3,4-c]pyridine-2-acetic acid derivative; Aminomethylpyrrolopyridinedione acetic acid
EINECS	Contact for details

Quality Control

Our 2H-Pyrrolo[3,4-C]Pyridine-2-Acetic Acid, 7-Amino-1,3-Dihydro--α-,6-Dimethyl-1,3-Dioxo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccant packs in secondary containers.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.