Description

6-Chloro-3-Aminopyridine-2-Carboxamide is a high-purity, multi-functional heterocyclic building block of significant commercial and research interest. Its molecular structure, featuring both chloro and amino substituents on the pyridine-carboxamide core, makes it a versatile intermediate for synthesizing complex molecules. This compound is primarily sought after by pharmaceutical, agrochemical, and fine chemical industries for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production in fine chemical manufacturing.
• Biochemical Research: Used as a molecular probe or intermediate in biochemical pathway studies and diagnostic agent development.

Basic Information

Product Name	6-Chloro-3-Aminopyridine-2-Carboxamide
CAS No.	175358-01-7
Molecular Formula	C6H6ClN3O
Molecular Weight	171.58 g/mol
Synonyms	2-Carbamoyl-6-chloropyridin-3-amine; 3-Amino-6-chloropyridine-2-carboxamide; 6-Chloro-3-aminopicolinamide; 6-Chloro-3-aminopyridine-2-carboxylic acid amide; 6-Chloro-3-pyridinamine-2-carboxamide; 2-Pyridinecarboxamide, 3-amino-6-chloro-; 3-Amino-6-chloro-2-pyridinecarboxamide
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Aminopyridine-2-Carboxamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.