Description

1-Benzyl-4-Bromo-1,2,3,6-Tetrahydropyridine is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex pharmacologically active molecules, enabling critical carbon-carbon and carbon-heteroatom bond formations. Pharmaceutical researchers and fine chemical manufacturers need it for constructing novel nitrogen-containing scaffolds, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those with piperidine or tetrahydropyridine core structures.
• Medicinal Chemistry Research: Used as a versatile building block for constructing novel chemical libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Serves as an intermediate in the development of new crop protection agents and pesticides.
• Ligand and Catalyst Development: Employed in the preparation of specialized nitrogen-based ligands for asymmetric catalysis and metal complexation.
• Chemical Biology Probes: Utilized to create tool compounds and molecular probes for studying biological pathways and enzyme functions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-Benzyl-4-Bromo-1,2,3,6-Tetrahydropyridine
CAS No.	175347-95-2
Molecular Formula	C12H14BrN
Molecular Weight	252.15 g/mol
Synonyms	4-Bromo-1-benzyl-1,2,3,6-tetrahydropyridine; 1-Benzyl-4-bromo-1,2,3,6-tetrahydropyridine; 1,2,3,6-Tetrahydro-1-benzyl-4-bromopyridine; 4-Bromo-1-benzyl-1,2,3,6-tetrahydropyridine; N-Benzyl-4-bromo-1,2,3,6-tetrahydropyridine; 4-Bromo-N-benzyl-3,6-dihydro-2H-pyridine; 175347-95-2
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4-Bromo-1,2,3,6-Tetrahydropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and adherence to ICH guidelines ensure a reliable supply for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.