Description

5-[5-(Trifluoromethyl)Pyrid-2-Yl]-1H-Tetrazole is a high-value heterocyclic compound featuring a pyridine ring linked to a tetrazole moiety, with a strategically positioned trifluoromethyl group. This structure makes it a versatile and critical pharmaceutical intermediate and agrochemical building block, prized for its ability to modulate the physicochemical properties of target molecules. It is primarily sought after by R&D and production teams in the life sciences and crop protection industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic disorders, inflammation, and central nervous system (CNS) diseases.
• Agrochemical Building Block: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand in Catalysis: Serves as a precursor for nitrogen-donor ligands in transition metal catalysis, facilitating various cross-coupling and organic transformation reactions.
• Material Science Research: Investigated as a component in the development of energetic materials, metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a bioisostere for carboxylic acids in drug design.

Basic Information

Item	Details
Product Name	5-[5-(Trifluoromethyl)Pyrid-2-Yl]-1H-Tetrazole
CAS No.	175334-70-0
Molecular Formula	C7H4F3N5
Molecular Weight	215.14 g/mol
Synonyms	5-(5-(Trifluoromethyl)pyridin-2-yl)-1H-tetrazole; 2-(1H-Tetrazol-5-yl)-5-(trifluoromethyl)pyridine; 5-(5-Trifluoromethyl-2-pyridyl)tetrazole; 5-(5-Trifluoromethylpyridin-2-yl)-1H-tetrazole; 2-Pyridinecarbonitrile, 5-(trifluoromethyl)-, 1-oxide (precursor); 5-(5-(Trifluoromethyl)-2-pyridinyl)-1H-tetrazole; 175334-70-0; 5-(5-Trifluoromethyl-2-pyridyl)-1H-tetrazole
EINECS	Contact for details

Quality Control

Our 5-[5-(Trifluoromethyl)Pyrid-2-Yl]-1H-Tetrazole is manufactured under a strict quality management system. All batches undergo rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with exacting R&D and production standards. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.