Description

Diethyl 3-Amino-6-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2,5-Dicarboxylate is a high-value, multifunctional heterocyclic building block characterized by its fused thienopyridine core and strategically positioned amino and trifluoromethyl groups. This compound is essential for advanced organic synthesis, offering a versatile scaffold for constructing complex molecular architectures with tailored electronic and steric properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• As a key synthetic intermediate in pharmaceutical research for the development of new drug candidates, particularly in kinase inhibitor and antiviral programs.
• In the synthesis of advanced agrochemicals, where the trifluoromethyl group enhances biological activity, metabolic stability, and lipophilicity.
• As a versatile precursor for functional materials and organic electronic components due to its electron-deficient heterocyclic structure.
• For the preparation of custom ligands and catalysts in metal-organic chemistry and catalysis research.
• In academic and industrial R&D for methodology development and the exploration of new heterocyclic coupling reactions.

Basic Information

Item	Details
Product Name	Diethyl 3-Amino-6-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2,5-Dicarboxylate
CAS No.	175277-75-5
Molecular Formula	C14H13F3N2O4S
Molecular Weight	362.32 g/mol
Synonyms	Diethyl 3-Amino-6-(trifluoromethyl)thieno[2,3-b]pyridine-2,5-dicarboxylate; 2,5-Diethyl 3-Amino-6-(trifluoromethyl)thieno[2,3-b]pyridine-2,5-dicarboxylate; 3-Amino-6-(trifluoromethyl)thieno[2,3-b]pyridine-2,5-dicarboxylic Acid Diethyl Ester; Ethyl 3-Amino-6-(trifluoromethyl)thieno[2,3-b]pyridine-2,5-dicarboxylate; CAS 175277-75-5
EINECS	Contact for details

Quality Control

Our production of Diethyl 3-Amino-6-(Trifluoromethyl)Thieno[2,3-B]Pyridine-2,5-Dicarboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and supporting regulatory documentation needs for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.