Description

Ethyl 2-Chloro-3-Cyano-6-(Trifluoromethyl)-Pyridine-5-Carboxylate is a high-value, multi-functional pyridine derivative that serves as a critical synthetic intermediate in advanced chemical manufacturing. Its unique trifluoromethyl and cyano substituents make it a versatile building block for constructing complex molecules with tailored properties. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical sectors seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Item	Details
Product Name	Ethyl 2-Chloro-3-Cyano-6-(Trifluoromethyl)-Pyridine-5-Carboxylate
CAS No.	175277-73-3
Molecular Formula	C10H6ClF3N2O2
Molecular Weight	278.62 g/mol
Synonyms	2-Chloro-3-cyano-6-(trifluoromethyl)pyridine-5-carboxylic acid ethyl ester; Ethyl 2-chloro-3-cyano-6-trifluoromethyl-5-pyridinecarboxylate; 5-Pyridinecarboxylic acid, 2-chloro-3-cyano-6-(trifluoromethyl)-, ethyl ester; 175277-73-3; 2-Chloro-3-cyano-6-(trifluoromethyl)nicotinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Chloro-3-Cyano-6-(Trifluoromethyl)-Pyridine-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support audits and can provide materials suitable for cGMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. The container must be kept tightly closed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.