Description

3-Amino-2,6-Dichloro-4-(Trifluoromethyl)Pyridine is a high-purity, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced chemical synthesis. This compound matters for its unique trifluoromethyl and amino-chloro substitution pattern, which imparts valuable electronic and steric properties to target molecules. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) and nucleophilic aromatic substitution to introduce complex pyridine scaffolds.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D focused on fluorinated heterocyclic chemistry and structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Amino-2,6-Dichloro-4-(Trifluoromethyl)Pyridine
CAS No.	175277-67-5
Molecular Formula	C7H3Cl2F3N2
Molecular Weight	255.01 g/mol
Synonyms	2,6-Dichloro-3-amino-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-3-amino-2,6-dichloropyridine; 3-Amino-2,6-dichloro-4-trifluoromethylpyridine; 2,6-Dichloro-4-(trifluoromethyl)pyridin-3-amine; Pyridine, 3-amino-2,6-dichloro-4-(trifluoromethyl)-; 175277-67-5
EINECS	Contact for details

Quality Control

Our 3-Amino-2,6-Dichloro-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.