Description

1-(5-Nitro-2-Pyridinyl)-4-(Trifluoromethyl)Piperidine is a high-value, nitrogen-containing heterocyclic compound featuring a nitro-substituted pyridine ring and a trifluoromethylated piperidine moiety. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and process chemistry teams in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Serves as a building block for developing novel pesticides and herbicides, leveraging the biological activity of the nitro-pyridine and trifluoromethyl groups.
• Medicinal Chemistry & SAR Studies: Used extensively in structure-activity relationship (SAR) studies to optimize the potency and pharmacokinetic properties of lead compounds.
• Chemical Synthesis: Employed in organic synthesis for constructing complex molecules, where its functional groups allow for further selective chemical transformations.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, ligands for catalysis, or advanced materials with specific electronic properties.

Basic Information

Product Name	1-(5-Nitro-2-Pyridinyl)-4-(Trifluoromethyl)Piperidine
CAS No.	175277-61-9
Molecular Formula	C11H12F3N3O2
Molecular Weight	275.23 g/mol
Synonyms	4-(Trifluoromethyl)-1-(5-nitro-2-pyridinyl)piperidine; 1-(5-Nitro-2-pyridyl)-4-(trifluoromethyl)piperidine; 4-(Trifluoromethyl)-1-(5-nitropyridin-2-yl)piperidine; 2-(4-(Trifluoromethyl)piperidin-1-yl)-5-nitropyridine; Piperidine, 1-(5-nitro-2-pyridinyl)-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 1-(5-Nitro-2-Pyridinyl)-4-(Trifluoromethyl)Piperidine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment ensures the material meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.