Description

3-Chloro-5-(trifluoromethyl)pyridine-2-thiocarboxamide is a high-value, multi-functional heterocyclic building block featuring a reactive thiocarboxamide group. This compound is critical for the synthesis of advanced agrochemicals and pharmaceuticals, where its unique halogenated pyridine core enables precise molecular design. It is primarily sought by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine-thioamide scaffold.
• Pharmaceutical Building Block: Used in medicinal chemistry for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting neurological and metabolic disorders.
• Ligand Synthesis: Serves as a versatile starting material for creating complex ligands used in catalysis and material science.
• Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways in heterocyclic chemistry.
• Specialty Chemical Production: Utilized in the manufacture of dyes, pigments, and other performance chemicals requiring a stable, halogenated pyridine structure.

Basic Information

Product Name	3-Chloro-5-(trifluoromethyl)pyridine-2-thiocarboxamide
CAS No.	175277-46-0
Molecular Formula	C7H4ClF3N2S
Molecular Weight	240.63 g/mol
Synonyms	2-Pyridinecarbothioamide, 3-chloro-5-(trifluoromethyl)-; 3-Chloro-5-trifluoromethylpyridine-2-carbothioamide; 3-Chloro-5-(trifluoromethyl)picolinothioamide; 2-Thiocarbamoyl-3-chloro-5-(trifluoromethyl)pyridine; 175277-46-0; 3-Chloro-5-(trifluoromethyl)-2-pyridinethiocarboxamide
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-(trifluoromethyl)pyridine-2-thiocarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.