Description

6-Acetyl-2-Mercaptonicotinonitrile is a versatile and high-value heterocyclic building block with a unique chemical structure. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on novel active ingredients, including potential kinase inhibitors and other nitrogen-containing heterocycles. The compound is supplied to global markets with a focus on consistent quality and reliable supply for critical R&D and scale-up projects.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other nitrogen-containing bioactive molecules.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Chemical Synthesis: Serves as a versatile precursor for constructing more complex pyridine and fused-ring systems in organic and medicinal chemistry.
• Material Science Research: Potential intermediate for the development of specialty chemicals, dyes, or functional materials requiring specific heterocyclic motifs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	6-Acetyl-2-Mercaptonicotinonitrile
CAS No.	175277-42-6
Molecular Formula	C8H6N2OS
Molecular Weight	178.21 g/mol
Synonyms	2-Mercapto-6-acetylpyridine-3-carbonitrile; 3-Cyano-2-mercapto-6-acetylpyridine; 6-Acetyl-2-mercapto-3-cyanopyridine; 2-Mercapto-6-acetyl-3-cyanopyridine; 6-Acetyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile; 2-Acetyl-5-cyano-6-mercaptopyridine; (6-Acetyl-2-mercapto-3-pyridyl)carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Acetyl-2-Mercaptonicotinonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.