Description

Ethyl 5-(4-Chlorophenyl)-2-(Trifluoromethyl)-3-Furoate is a high-value, multi-functional chemical intermediate characterized by its unique furan ring core substituted with chlorophenyl and trifluoromethyl groups. This molecular architecture makes it a critical building block for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), offering significant advantages in tuning lipophilicity and metabolic stability. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the furan and trifluoromethyl motifs.
• Material Science Research: Used in the development of organic electronic materials, liquid crystals, and advanced polymers due to its rigid, aromatic structure.
• Chemical Research & Development: Employed in academic and industrial labs for methodology development and the creation of complex molecular libraries.
• Custom Synthesis & Contract Manufacturing: A pivotal starting material for custom synthesis projects requiring specific fluorinated and chlorinated heterocycles.

Basic Information

Product Name	Ethyl 5-(4-Chlorophenyl)-2-(Trifluoromethyl)-3-Furoate
CAS No.	175276-59-2
Molecular Formula	C14H10ClF3O3
Molecular Weight	318.68 g/mol
Synonyms	Ethyl 5-(4-chlorophenyl)-2-(trifluoromethyl)furan-3-carboxylate; 3-Furancarboxylic acid, 5-(4-chlorophenyl)-2-(trifluoromethyl)-, ethyl ester; 5-(4-Chlorophenyl)-2-(trifluoromethyl)-3-furoic acid ethyl ester; Ethyl 5-(p-chlorophenyl)-2-(trifluoromethyl)-3-furoate
EINECS	Contact for details

Quality Control

Our Ethyl 5-(4-Chlorophenyl)-2-(Trifluoromethyl)-3-Furoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.