Description

Cyclopropaneacetic Acid, 2-(Methoxycarbonyl)-, trans- (9Ci) is a high-purity, specialized chiral building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and complex agrochemicals, where its defined stereochemistry is critical for efficacy. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct complex molecular architectures with precision.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the trans-configuration imparts specific biological activity.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrance and flavor ingredients requiring high stereochemical purity.
• Material Science Monomer: Potential use as a specialty monomer for creating polymers with unique cyclic structures and properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including ring-opening and cross-coupling reactions.

Basic Information

Product Name	Cyclopropaneacetic Acid, 2-(Methoxycarbonyl)-, trans- (9Ci)
CAS No.	175221-16-6
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	trans-2-(Methoxycarbonyl)cyclopropaneacetic Acid; (1R,2S)-rel-2-(Carboxymethyl)cyclopropanecarboxylic Acid Methyl Ester; Methyl (1R,2S)-rel-2-(Carboxymethyl)cyclopropanecarboxylate; trans-Methyl 2-(carboxymethyl)cyclopropanecarboxylate; Cyclopropaneacetic acid, 2-(methoxycarbonyl)-, trans-; 175221-16-6; (1R,2S)-2-(Methoxycarbonyl)cyclopropaneacetic acid
EINECS	Contact for details

Quality Control

Our Cyclopropaneacetic Acid, 2-(Methoxycarbonyl)-, trans- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC to confirm stereochemical purity and identity verification by NMR and IR spectroscopy. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.