Description

(4S)-(4-Fluorophenoxy)Methyl Butyrolactone is a high-purity chiral building block and pharmaceutical intermediate. This compound is valued for its defined stereochemistry and functional group versatility, enabling precise synthesis in complex organic molecules. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and other advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Synthesis: Used as a starting material or reagent in stereoselective reactions to construct complex molecular architectures.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring high enantiomeric purity.
• Academic & Industrial R&D: Serves as a critical reagent in medicinal chemistry programs and process development for scale-up.
• Ligand and Catalyst Development: Potential precursor for creating novel chiral ligands or organocatalysts used in catalytic asymmetric transformations.

Basic Information

Product Name	(4S)-(4-Fluorophenoxy)Methyl Butyrolactone
CAS No.	175212-40-5
Molecular Formula	C11H11FO3
Molecular Weight	210.20 g/mol
Synonyms	(S)-γ-(4-Fluorophenoxy)methyl-γ-butyrolactone; (4S)-4-[(4-Fluorophenoxy)methyl]dihydrofuran-2(3H)-one; (S)-4-(4-Fluorophenoxymethyl)butyrolactone; (S)-4-(p-Fluorophenoxymethyl)-γ-butyrolactone; (S)-γ-(p-Fluorophenoxy)methyl-γ-butyrolactone; (4S)-4-[(4-Fluorophenoxy)methyl]-2-oxolanone; (S)-4-(4-Fluorobenzyloxy)butyrolactone (common misnomer).
EINECS	Contact for details

Quality Control

Our (4S)-(4-Fluorophenoxy)Methyl Butyrolactone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.