Description

Glycine, n-[(1,1-Dimethylethoxy)Carbonyl]-n-(2-Oxoethyl)-Methyl Ester CAS NO 175211-73-1 is a specialized Boc-protected glycine derivative, serving as a crucial protected amino acid building block in advanced organic synthesis. Its primary value lies in enabling the controlled, sequential construction of complex peptides and other bioactive molecules by protecting the amine functionality during reactions. This high-purity intermediate is essential for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced material science who require reliable, high-quality synthetic precursors.

Application

• Pharmaceutical Intermediate: A key protected building block for the solid-phase and solution-phase synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of specialized amino acid-derived herbicides, fungicides, and plant growth regulators.
• Bioconjugation & Linker Chemistry: Facilitates the site-specific modification of proteins, antibodies, and other biomolecules for diagnostic and therapeutic applications.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes, enzyme substrates, and other tools for studying biological pathways.
• Material Science: Acts as a monomer or modifying agent in the synthesis of functional polymers and smart materials with specific surface properties.
• Academic & Industrial R&D: Serves as a fundamental reagent for methodological development in organic chemistry and medicinal chemistry laboratories worldwide.

Basic Information

Product Name	Glycine, n-[(1,1-Dimethylethoxy)Carbonyl]-n-(2-Oxoethyl)-Methyl Ester
CAS No.	175211-73-1
Molecular Formula	C10H17NO5
Molecular Weight	231.25 g/mol
Synonyms	Boc-Glycine(oxoethyl) methyl ester; N-(tert-Butoxycarbonyl)-N-(2-oxoethyl)glycine methyl ester; Methyl N-[(1,1-dimethylethoxy)carbonyl]-N-(2-oxoethyl)glycinate; N-Boc-N-(2-oxoethyl)glycine methyl ester; Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-(2-oxoethyl)-, methyl ester; Boc-Gly-OEt(oxo)-OMe; (tert-Butoxycarbonyl)(2-oxoethyl)aminoacetic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Glycine, n-[(1,1-Dimethylethoxy)Carbonyl]-n-(2-Oxoethyl)-Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.