Description

2-Bromo-3-Trifluoromethylpyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining bromine and a trifluoromethyl group on the pyridine ring, enables precise molecular modifications essential for developing novel compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides, where the trifluoromethyl group often improves metabolic stability and bioavailability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and liquid crystal materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Ligand and Catalyst Development: Utilized to synthesize complex nitrogen-containing ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A valuable compound for research into the effects of fluorine substitution on the physicochemical properties of heterocyclic systems.

Basic Information

Product Name	2-Bromo-3-Trifluoromethylpyridine
CAS No.	175205-82-0
Molecular Formula	C6H3BrF3N
Molecular Weight	225.99 g/mol
Synonyms	3-Trifluoromethyl-2-bromopyridine; 2-Bromo-3-(trifluoromethyl)pyridine; Pyridine, 2-bromo-3-(trifluoromethyl)-; 2-Bromo-α,α,α-trifluoro-3-picoline
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Trifluoromethylpyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.