Description

4-(Trifluoromethyl)Pyridine-3-Carboxamide Oxime is a specialized fluorinated pyridine derivative, a high-value intermediate prized for its unique chemical reactivity and structural motif. This compound is critical for the synthesis of advanced molecules in life sciences, where the trifluoromethyl and oxime functionalities are key to modulating biological activity and physicochemical properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Ligand and Chelator Precursor: Serves as a starting material for synthesizing specialized ligands used in catalysis or metal complexation studies.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and creating libraries of fluorinated heterocyclic compounds.
• Material Science Applications: Potential use as a monomer or functional additive in the synthesis of advanced polymers with specific surface properties.

Basic Information

Product Name	4-(Trifluoromethyl)Pyridine-3-Carboxamide Oxime
CAS No.	175204-85-0
Molecular Formula	C7H6F3N3O
Molecular Weight	205.14 g/mol
Synonyms	3-(Aminocarbonyl)-4-(trifluoromethyl)pyridine oxime; 4-(Trifluoromethyl)-3-pyridinecarboxamide oxime; 3-Carbamoyl-4-(trifluoromethyl)pyridine oxime; 4-Trifluoromethylnicotinamide oxime; Pyridine-3-carboxamide, 4-(trifluoromethyl)-, oxime; (Z)-N'-hydroxy-4-(trifluoromethyl)pyridine-3-carboximidamide; (E)-N'-hydroxy-4-(trifluoromethyl)pyridine-3-carboximidamide
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Pyridine-3-Carboxamide Oxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to cGMP and ISO guidelines ensures reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.