Description

Methyl 4-(Trifluoromethyl)Nicotinate CAS NO 175204-82-7 is a high-purity trifluoromethyl-substituted nicotinate derivative, a key building block in advanced organic synthesis. Its value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the versatile methyl ester functionality, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals with tailored optical or electronic properties.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, enzyme inhibitors, and labeled compounds for biochemical research.
• Fine Chemical Production: Integral to custom synthesis and contract manufacturing of complex, high-value organic molecules for various industrial applications.

Basic Information

Product Name	Methyl 4-(Trifluoromethyl)Nicotinate
CAS No.	175204-82-7
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	Methyl 4-(trifluoromethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 4-(trifluoromethyl)-, methyl ester; 4-(Trifluoromethyl)nicotinic acid methyl ester; Methyl 4-trifluoromethylnicotinate; 175204-82-7; Methyl 4-(trifluoromethyl)-3-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4-(Trifluoromethyl)Nicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.