Description

4-(Bromomethyl)-2,6-Dichloropyridine is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromomethyl and dichloro substituents, makes it an exceptionally valuable intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing antimicrobial properties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromomethyl group is an excellent handle for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to introduce complex side chains.
• Nucleophilic Substitution Scaffold: The halogenated sites allow for sequential functionalization, enabling the construction of diverse chemical libraries for screening.

Basic Information

Product Name	4-(Bromomethyl)-2,6-Dichloropyridine
CAS No.	175204-45-2
Molecular Formula	C7H4BrCl2N
Molecular Weight	264.92 g/mol
Synonyms	2,6-Dichloro-4-(bromomethyl)pyridine; 4-(Bromomethyl)-2,6-dichloropyridine; 2,6-Dichloro-4-pyridinemethanol, bromide; Pyridine, 4-(bromomethyl)-2,6-dichloro-; (2,6-Dichloro-4-pyridyl)methyl bromide
EINECS	Contact for details

Quality Control

Every batch of 4-(Bromomethyl)-2,6-Dichloropyridine is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.