Description

5-(2-Phenyleth-1-Ynyl)Nicotinic Acid (CAS NO 175203-69-7) is a high-purity organic building block featuring a nicotinic acid core functionalized with a phenylethynyl group. This compound is valued for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products.
• Material Science: Serves as a precursor for organic electronic materials and liquid crystals due to its conjugated structure.
• Chemical Synthesis: A versatile reagent for Sonogashira and other cross-coupling reactions to create complex molecular architectures.
• Academic & Institutional R&D: Employed in universities and research institutes for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	5-(2-Phenyleth-1-Ynyl)Nicotinic Acid
CAS No.	175203-69-7
Molecular Formula	C14H9NO2
Molecular Weight	223.23 g/mol
Synonyms	5-[(2-Phenylethynyl)]nicotinic acid; 3-Pyridinecarboxylic acid, 5-(2-phenylethynyl)-; Nicotinic acid, 5-(2-phenylethynyl)-; 5-(Phenylethynyl)nicotinic acid; 5-(2-Phenylethynyl)pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(2-Phenyleth-1-Ynyl)Nicotinic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.