Description

Ethyl 5-(2-Phenyleth-1-Ynyl)Nicotinate is a specialized organic compound belonging to the nicotinate ester family, featuring a phenylacetylene substituent. This structural motif makes it a valuable high-purity intermediate for advanced chemical synthesis, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological or inflammatory pathways.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides due to its bioactive nicotinate core.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Ligand Synthesis: Utilized in organometallic chemistry for the preparation of specialized ligands in catalysis.
• Chemical Biology Probe: Acts as a scaffold for developing molecular probes to study biological processes.
• Academic & Industrial R&D: Fundamental research compound in synthetic organic chemistry for methodology development and library synthesis.

Basic Information

Product Name	Ethyl 5-(2-Phenyleth-1-Ynyl)Nicotinate
CAS No.	175203-65-3
Molecular Formula	C₁₆H₁₃NO₂
Molecular Weight	251.28 g/mol
Synonyms	Ethyl 5-(2-phenylethynyl)nicotinate; 5-(2-Phenylethynyl)nicotinic Acid Ethyl Ester; Nicotinic acid, 5-(2-phenylethynyl)-, ethyl ester; 3-Pyridinecarboxylic acid, 5-(2-phenylethynyl)-, ethyl ester; Ethyl 5-(phenylethynyl)nicotinate
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.