Description

5-[3-Chloro-5-(Trifluoromethyl)Pyrid-2-Ylsulphonyl]Thiophene-2-Sulphonyl Chloride is a high-purity, advanced pharmaceutical intermediate characterized by its reactive sulphonyl chloride groups and halogenated heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based therapeutics. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of sulfonamide-based drug candidates targeting various disease pathways.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides with specific modes of action.
• Material Science Research: Serves as a precursor for creating functionalized polymers or specialty chemicals with unique surface properties.
• Chemical Biology Probes: Utilized in the development of molecular probes and inhibitors for enzyme and receptor studies.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	5-[3-Chloro-5-(Trifluoromethyl)Pyrid-2-Ylsulphonyl]Thiophene-2-Sulphonyl Chloride
CAS No.	175203-00-6
Molecular Formula	C11H4Cl2F3NO4S3
Molecular Weight	455.25 g/mol
Synonyms	5-[(3-Chloro-5-(trifluoromethyl)-2-pyridinyl)sulfonyl]-2-thiophenesulfonyl chloride; 2-Thiophenesulfonyl chloride, 5-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]sulfonyl]-; 5-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)sulfonyl)thiophene-2-sulfonyl chloride; 175203-00-6; CAS-175203-00-6
EINECS	Contact for details

Quality Control

Every batch of 5-[3-Chloro-5-(Trifluoromethyl)Pyrid-2-Ylsulphonyl]Thiophene-2-Sulphonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.