Description

Azetidine,1-(2-Pyrrolidinylcarbonyl)-,(S)-(9Ci) is a high-purity, chiral azetidine derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Asymmetric Synthesis: Employed as a precursor or catalyst ligand in stereoselective reactions to introduce the azetidine moiety with high enantiomeric purity.
• Peptidomimetics & Bioisosteres: Used to design and synthesize novel peptide analogs where the azetidine ring acts as a conformationally restricted proline surrogate.
• Agrochemical Research: Building block for developing new generation pesticides and herbicides with improved efficacy and selectivity.
• Material Science: Potential monomer or functional additive in the synthesis of specialized polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying enzyme mechanisms and protein-protein interactions.

Basic Information

Product Name	Azetidine,1-(2-Pyrrolidinylcarbonyl)-,(S)-(9Ci)
CAS No.	175155-21-2
Molecular Formula	C8H12N2O
Molecular Weight	152.20 g/mol
Synonyms	(S)-1-(Pyrrolidine-2-carbonyl)azetidine; 1-[(2S)-2-Pyrrolidinylcarbonyl]azetidine; (S)-Azetidin-1-yl(pyrrolidin-2-yl)methanone; Azetidine, 1-(2-pyrrolidinylcarbonyl)-, (S)-; (S)-N-(Azetidin-1-yl)pyrrolidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our Azetidine,1-(2-Pyrrolidinylcarbonyl)-,(S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.