Description

Imidazo[1,2-A]Pyridine-5-Thiol, 2-Methyl- is a high-value heterocyclic building block and sulfur-containing intermediate. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical sector, due to its unique fused-ring structure and reactive thiol group. It is primarily utilized by research institutions and manufacturers in the life sciences and advanced materials industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting the central nervous system, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in conductive polymers.
• Chemical Biology Probes: Employed in the design of probes and inhibitors for studying enzyme mechanisms and protein interactions due to the reactive thiol moiety.
• Catalyst Ligand Synthesis: Used to create specialized ligands for transition metal catalysis in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the pharmaceutical and biotechnology sectors.

Basic Information

Product Name	Imidazo[1,2-A]Pyridine-5-Thiol, 2-Methyl-
CAS No.	175143-70-1
Molecular Formula	C8H8N2S
Molecular Weight	164.23 g/mol
Synonyms	2-Methylimidazo[1,2-a]pyridine-5-thiol; 2-Methyl-5-mercaptoimidazo[1,2-a]pyridine; 5-Mercapto-2-methylimidazo[1,2-a]pyridine; 2-Methyl-5-sulfanylidene-5,7-dihydroimidazo[1,2-a]pyridine; 2-Methylimidazo[1,2-a]pyridine-5-thione; Imidazo[1,2-a]pyridine-5-thiol, 2-methyl-; 175143-70-1
EINECS	Contact for details

Quality Control

Our Imidazo[1,2-A]Pyridine-5-Thiol, 2-Methyl- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.