Description

Ethyl 2-(4-Nitrophenyl)-3-(Trifluoromethyl)Pyrazole-4-Carboxylate is a high-value, multi-functional pyrazole derivative that serves as a critical synthetic intermediate. Its molecular architecture, featuring both a nitroaryl and a trifluoromethyl group, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting inflammation, metabolic disorders, and central nervous system (CNS) diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or a scaffold for developing enzyme inhibitors and other bioactive tools.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, cyclizations, and other transformations to introduce complex pyrazole motifs into target molecules.

Basic Information

Product Name	Ethyl 2-(4-Nitrophenyl)-3-(Trifluoromethyl)Pyrazole-4-Carboxylate
CAS No.	175137-35-6
Molecular Formula	C13H10F3N3O4
Molecular Weight	329.23 g/mol
Synonyms	Ethyl 2-(4-nitrophenyl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxylate; 4-Carbethoxy-2-(4-nitrophenyl)-3-(trifluoromethyl)pyrazole; 1H-Pyrazole-4-carboxylic acid, 2-(4-nitrophenyl)-3-(trifluoromethyl)-, ethyl ester; Ethyl 2-(p-nitrophenyl)-3-(trifluoromethyl)pyrazole-4-carboxylate; 175137-35-6; 2-(4-Nitrophenyl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-(4-Nitrophenyl)-3-(Trifluoromethyl)Pyrazole-4-Carboxylate adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.