Description

2-Chloro-3,6-Bis(trifluoromethyl)pyridine is a high-value, multi-functional fluorinated pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the unique reactivity imparted by the chlorine and trifluoromethyl groups, enabling precise molecular construction for demanding applications. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, where it is used to build complex active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the pyridine core and fluorine atoms contribute to efficacy and environmental profile.
• Ligand and Catalyst Precursor: Serves as a starting material for creating specialized ligands used in catalysis, including cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of fluorinated organic electronic materials, such as components for OLEDs or semiconductors, where fluorine substitution tunes electronic properties.
• Custom Synthesis and Contract Manufacturing: A vital substrate for fine chemical and custom synthesis houses serving the life science and specialty chemical markets.

Basic Information

Product Name	2-Chloro-3,6-Bis(trifluoromethyl)pyridine
CAS No.	175136-26-2
Molecular Formula	C7H2ClF6N
Molecular Weight	249.54 g/mol
Synonyms	2-Chloro-3,6-bis(trifluoromethyl)pyridine; 3,6-Bis(trifluoromethyl)-2-chloropyridine; 2-Chloro-3,6-di(trifluoromethyl)pyridine; Pyridine, 2-chloro-3,6-bis(trifluoromethyl)-; 175136-26-2; 2-Chloro-α,α,α,α',α',α'-hexafluoro-3,6-lutidine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3,6-Bis(trifluoromethyl)pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.