Description

3-Chloro-2-Methoxy-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its unique molecular architecture, combining a halogenated pyridine core with methoxy and trifluoromethyl substituents, which enables precise structural modifications in target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for functionalized ligands in catalysis and for creating specialty polymers with tailored electronic properties.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical spaces, structure-activity relationships (SAR), and novel synthetic methodologies.
• Liquid Crystal & OLED Materials: Acts as a fluorinated component in the synthesis of advanced electronic materials for displays and lighting applications.

Basic Information

Product Name	3-Chloro-2-Methoxy-5-(Trifluoromethyl)Pyridine
CAS No.	175136-17-1
Molecular Formula	C7H5ClF3NO
Molecular Weight	211.57 g/mol
Synonyms	2-Methoxy-3-chloro-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-3-chloro-2-methoxypyridine; 3-Chloro-2-methoxy-5-trifluoromethylpyridine; 2-Methoxy-3-chloro-5-trifluoromethylpyridine; Pyridine, 3-chloro-2-methoxy-5-(trifluoromethyl)-; 175136-17-1
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2-Methoxy-5-(Trifluoromethyl)Pyridine is produced under a strict quality management system and undergoes rigorous analytical testing to ensure high purity, consistency, and traceability. Our standard grade meets typical R&D and process development requirements, with specifications verified by HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support custom synthesis and can tailor purity specifications to meet specific project needs, including cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.