Description

2-[(4-Methylphenyl)Thio]Nicotinamide is a specialized organic compound featuring a nicotinamide core modified with a (4-methylphenyl)thio substituent. This structural motif makes it a valuable intermediate in advanced pharmaceutical research and fine chemical synthesis. It is primarily sought after by research institutions and chemical manufacturers engaged in the development of novel bioactive molecules, particularly in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting enzyme inhibition.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new therapeutic agents.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories.
• Organic Synthesis: Versatile precursor for constructing complex heterocyclic compounds and functionalized aromatics.
• Biochemical Research: Potential tool compound for studying biological pathways involving nicotinamide analogs.

Basic Information

Product Name	2-[(4-Methylphenyl)Thio]Nicotinamide
CAS No.	175135-83-8
Molecular Formula	C13H12N2OS
Molecular Weight	244.31 g/mol
Synonyms	2-[(4-Methylphenyl)sulfanyl]pyridine-3-carboxamide; 2-(p-Tolylthio)nicotinamide; Nicotinamide, 2-[(4-methylphenyl)thio]-; 3-Pyridinecarboxamide, 2-[(4-methylphenyl)thio]-; 2-(4-Methylphenylthio)nicotinamide; 2-(4-Methylbenzenethio)nicotinamide
EINECS	Contact for details

Quality Control

Our 2-[(4-Methylphenyl)Thio]Nicotinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.