Description

2-(2-Fluorophenoxy)-3-Nitropyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct fluorinated aromatic ether and nitropyridine structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for creating novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorophenoxy and nitro functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorophenoxy moiety can contribute to biological activity and environmental stability.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands and functionalized polymers for advanced materials.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific fluorinated nitropyridine scaffold.

Basic Information

Product Name	2-(2-Fluorophenoxy)-3-Nitropyridine
CAS No.	175135-65-6
Molecular Formula	C11H7FN2O3
Molecular Weight	234.19 g/mol
Synonyms	3-Nitro-2-(2-fluorophenoxy)pyridine; 2-(2-Fluorophenoxy)-3-nitropyridine; Pyridine, 2-(2-fluorophenoxy)-3-nitro-; 2-(2-Fluorophenoxy)-3-nitro-pyridine; 175135-65-6; 2-(o-Fluorophenoxy)-3-nitropyridine; 3-Nitro-2-(o-fluorophenoxy)pyridine
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Fluorophenoxy)-3-Nitropyridine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.