Description

3-Amino-2-(2,4-difluorophenoxy)pyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a pyridine core with a difluorophenoxy substituent, making it an essential intermediate for constructing complex pharmacologically active molecules. This compound is critically needed by research and development teams in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the bioactivity of the difluorophenoxy moiety.
• Material Science Research: Serves as a precursor for creating specialized ligands and functional organic molecules for advanced materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated heterocycles.

Basic Information

Product Name	3-Amino-2-(2,4-difluorophenoxy)pyridine
CAS No.	175135-63-4
Molecular Formula	C11H8F2N2O
Molecular Weight	222.19 g/mol
Synonyms	2-(2,4-Difluorophenoxy)-3-pyridinamine; 3-Pyridinamine, 2-(2,4-difluorophenoxy)-; 3-Amino-2-(2,4-difluorophenoxy)pyridine; 2-(2,4-Difluorophenoxy)pyridin-3-amine; 175135-63-4; 3-Amino-2-(2,4-difluorophenoxy)pyridine CAS NO 175135-63-4
EINECS	Contact for details

Quality Control

Our 3-Amino-2-(2,4-difluorophenoxy)pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture and oxidation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.