Description

Methyl 2-(6-Aminopyridin-3-Yl)Acetate is a high-purity, versatile pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional reactivity, featuring both a reactive ester group and a primary amine, enabling its use in the construction of complex molecular architectures. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging the pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of functional polymers, dyes, and photoactive materials.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes and bioconjugates for diagnostic and research applications.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	Methyl 2-(6-Aminopyridin-3-Yl)Acetate
CAS No.	174891-02-2
Molecular Formula	C8H10N2O2
Molecular Weight	166.18 g/mol
Synonyms	Methyl (6-Amino-3-pyridinyl)acetate; 3-Pyridineacetic acid, 6-amino-, methyl ester; Methyl 2-(6-Amino-3-pyridyl)acetate; 6-Aminonicotinic acid methyl ester derivative; 2-(6-Aminopyridin-3-yl)acetic acid methyl ester; Methyl 2-(6-aminopyridin-3-yl)acetate; (6-Aminopyridin-3-yl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-(6-Aminopyridin-3-Yl)Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.