Description

tert-Butyl 4-(2-Hydroxyphenyl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of new therapeutic agents. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapies.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for constructing complex piperidine-containing molecular scaffolds.
• Research & Development (R&D): Essential for academic and industrial research in pharmacology and organic chemistry.
• Process Chemistry: Used in scale-up and optimization studies for the commercial production of target molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	tert-Butyl 4-(2-Hydroxyphenyl)Piperidine-1-Carboxylate
CAS No.	174822-86-7
Molecular Formula	C16H23NO3
Molecular Weight	277.36 g/mol
Synonyms	1-Boc-4-(2-hydroxyphenyl)piperidine; 4-(2-Hydroxyphenyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(2-hydroxyphenyl)piperidine; tert-Butyl 4-(2-hydroxyphenyl)-1-piperidinecarboxylate; 4-(2-Hydroxyphenyl)piperidine-1-carboxylic acid tert-butyl ester; 1-Boc-4-(2-hydroxy-phenyl)piperidine; BOC-4-(2-Hydroxyphenyl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Hydroxyphenyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.