Description

(S)-3-(2-Azetidinylmethoxy)Pyridine 2Hcl is a high-purity chiral building block and pharmaceutical intermediate. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical suppliers serving the life sciences sector.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and neurological disorder targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Ligand and Receptor Studies: Employed in the development of selective ligands for nicotinic acetylcholine receptors (nAChRs) and other biological targets.
• Asymmetric Synthesis: Serves as a chiral precursor or auxiliary in enantioselective synthesis routes.
• Process Chemistry Development: Used for scaling up and optimizing synthetic routes for potential drug candidates in pre-clinical and clinical development.

Basic Information

Product Name	(S)-3-(2-Azetidinylmethoxy)Pyridine 2Hcl
CAS No.	174740-86-4
Molecular Formula	C9H14Cl2N2O
Molecular Weight	237.13 g/mol
Synonyms	(S)-3-[(Azetidin-2-yl)methoxy]pyridine dihydrochloride; (S)-3-(2-Azetidinylmethoxy)pyridine hydrochloride; (S)-3-(Azetidin-2-ylmethoxy)pyridine dihydrochloride; Pyridine, 3-[(2S)-2-azetidinylmethoxy]-, dihydrochloride; (S)-3-(Azetidin-2-ylmethoxy)pyridine 2HCl; (S)-3-(2-Azetidinylmethoxy)pyridine 2HCl; (S)-3-(Azetidin-2-ylmethoxy)pyridine HCl salt
EINECS	Contact for details

Quality Control

Our (S)-3-(2-Azetidinylmethoxy)Pyridine 2Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.