Description

2-Furancarboxylicacid,Tetrahydro-5-Methoxy-,Methylester,(2R-Trans)-(9Ci) is a high-purity, chiral tetrahydrofuran derivative that serves as a critical building block in advanced organic synthesis. Its defined stereochemistry and functionalized ring structure make it an invaluable intermediate for creating complex molecules with specific biological activities. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its stereochemistry can influence biological efficacy.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic processes to induce enantioselectivity.
• Fine Chemical Production: Serves as a starting material for specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2-Furancarboxylicacid,Tetrahydro-5-Methoxy-,Methylester,(2R-Trans)-(9Ci)
CAS No.	174689-91-9
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	(2R-trans)-Tetrahydro-5-methoxy-2-furancarboxylic acid methyl ester; Methyl (2R,5R)-5-methoxytetrahydro-2-furoate; Methyl (2R-trans)-5-methoxytetrahydrofuran-2-carboxylate; (2R,5R)-5-Methoxytetrahydro-2-furancarboxylic acid methyl ester; Tetrahydro-5-methoxy-2-furancarboxylic acid methyl ester, (2R-trans)-; 174689-91-9; (2R,5R)-Methyl 5-methoxytetrahydrofuran-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 2-Furancarboxylicacid,Tetrahydro-5-Methoxy-,Methylester,(2R-Trans)-(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.