Description

2-Furancarboxylicacid,Tetrahydro-5-Methoxy-,Methylester,(2S-Cis)-(9Ci) is a high-purity chiral intermediate of significant value in advanced organic synthesis. Its defined stereochemistry and functionalized tetrahydrofuran core make it a critical building block for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the construction of complex, stereochemically defined molecules for agrochemicals, flavors, and fragrances.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new catalytic systems.
• Academic & Industrial R&D: Employed in medicinal chemistry programs and process chemistry for route scouting and optimization.
• Specialty Polymer Chemistry: Potential monomer or modifier for creating polymers with specific functional or optical properties.

Basic Information

Product Name	2-Furancarboxylicacid,Tetrahydro-5-Methoxy-,Methylester,(2S-Cis)-(9Ci)
CAS No.	174563-65-6
Molecular Formula	C8H12O4
Molecular Weight	172.18 g/mol
Synonyms	(2S,5S)-5-Methoxy-2-tetrahydrofuroic acid methyl ester; Methyl (2S,5S)-5-methoxy-2-tetrahydrofuroate; (2S-cis)-Tetrahydro-5-methoxy-2-furancarboxylic acid methyl ester; 2(S),5(S)-Tetrahydro-5-methoxy-2-furancarboxylic acid methyl ester; (2S,5S)-Tetrahydro-5-methoxy-2-furancarboxylic acid methyl ester; Methyl (2S-cis)-5-methoxy-2-tetrahydrofuroate; Tetrahydro-5-methoxy-2-furancarboxylic acid methyl ester, (2S-cis)-
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Every lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/GC), chiral purity, and impurity profiles. We operate under a cGMP-compliant quality management system suitable for pharmaceutical applications, ensuring traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.