Description

4-(2-Chloroisonicotinoyl)Morpholine is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. Its core value lies in its utility as a versatile synthon for constructing complex nitrogen-containing heterocycles, which are pivotal in modern drug discovery. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific chlorinated nicotinamide scaffolds.
• Chemical Synthesis: Serves as a versatile precursor for creating complex morpholine and pyridine derivatives in medicinal chemistry.
• Material Science: Potential monomer or modifier in the development of specialty polymers and functional materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and scale-up services for client projects.
• Academic & Institutional Research: Used in university and government labs for fundamental studies in organic methodology and heterocyclic chemistry.

Basic Information

Product Name	4-(2-Chloroisonicotinoyl)Morpholine
CAS No.	174482-98-5
Molecular Formula	C10H11ClN2O2
Molecular Weight	226.66 g/mol
Synonyms	2-Chloro-4-(morpholine-4-carbonyl)pyridine; Morpholine, 4-[(2-chloro-4-pyridinyl)carbonyl]-; 4-(2-Chloropyridine-4-carbonyl)morpholine; 2-Chloroisonicotinoyl morpholine; 4-(2-Chloro-4-pyridinecarbonyl)morpholine; 2-Chloro-4-morpholinocarbonylpyridine
EINECS	Contact for details

Quality Control

Our 4-(2-Chloroisonicotinoyl)Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.