Description

1-Oxa-9-Azaspiro[5.5]Undecan-5-Ol is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries seeking to develop novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, especially for neurological and antiviral applications.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new bioactive molecules.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up API manufacturing under GMP conditions.
• Academic & Contract Research: Employed in university and CRO laboratories for the development of new synthetic methodologies and heterocyclic chemistry.
• Pre-clinical Drug Development: Integral to the synthesis of compounds for pharmacological screening and pre-clinical evaluation.

Basic Information

Product Name	1-Oxa-9-Azaspiro[5.5]Undecan-5-Ol
CAS No.	174469-91-1
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	1-Oxa-9-azaspiro[5.5]undecan-5-ol; 9-Aza-1-oxaspiro[5.5]undecan-5-ol; 5-Hydroxy-1-oxa-9-azaspiro[5.5]undecane; Spirocyclic amino alcohol intermediate; Oxa-azaspiro undecanol
EINECS	Contact for details

Quality Control

Our 1-Oxa-9-Azaspiro[5.5]Undecan-5-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for pharmaceutical R&D and development. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.