Description

3-Iodo-2-Pyridinyl-Carbamic Acid, 1,1-Dimethylethyl Ester is a specialized organic building block featuring a halogenated pyridine core protected by a tert-butyl carbamate group. This compound is valued for its role as a key synthetic intermediate in the development of complex molecules, particularly in pharmaceutical research and fine chemical synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing functionalized pyridine motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the iodo-pyridine unit is integral to biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers that require halogenated aromatic building blocks.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions, such as Suzuki, Stille, and Sonogashira couplings.
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) protecting group allows for selective deprotection in multi-step synthetic sequences.

Basic Information

Product Name	3-Iodo-2-Pyridinyl-Carbamic Acid, 1,1-Dimethylethyl Ester
CAS No.	174467-36-8
Molecular Formula	C10H13IN2O2
Molecular Weight	320.13 g/mol
Synonyms	tert-Butyl 3-iodopyridin-2-ylcarbamate; 2-Pyridinylcarbamic acid, 3-iodo-, 1,1-dimethylethyl ester; 3-Iodo-2-pyridylcarbamic acid tert-butyl ester; N-Boc-3-iodo-2-aminopyridine; Boc-3-Iodo-2-aminopyridine; 3-Iodo-N-Boc-2-aminopyridine; (3-Iodopyridin-2-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-Iodo-2-Pyridinyl-Carbamic Acid, 1,1-Dimethylethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if necessary and opened only in a moisture-controlled environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.