Description

1,4-Dioxaspiro[4.4]Nonane-6-Carboxylicacid,6-Fluoro-,(-)-(9Ci) is a high-purity, chiral fluorinated spirocyclic building block of significant interest in advanced organic synthesis. Its unique stereochemistry and functional group arrangement make it a critical intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily utilized by pharmaceutical R&D and fine chemical sectors for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Building block for creating advanced, enantiomerically pure herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials with tailored optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, exploring new fluorination and spirocyclization reactions.

Basic Information

Product Name	1,4-Dioxaspiro[4.4]Nonane-6-Carboxylicacid,6-Fluoro-,(-)-(9Ci)
CAS No.	174460-68-5
Molecular Formula	C9H11FO4
Molecular Weight	202.18 g/mol
Synonyms	(-)-6-Fluoro-1,4-dioxaspiro[4.4]nonane-6-carboxylic acid; (6S)-6-Fluoro-1,4-dioxaspiro[4.4]nonane-6-carboxylic acid; 6-Fluoro-1,4-dioxaspiro[4.4]nonane-6-carboxylic acid, (-)-; (6S)-6-Fluoro-1,4-dioxaspiro[4.4]nonane-6-carboxylicacid; 174460-68-5; (S)-6-Fluoro-1,4-dioxaspiro[4.4]nonane-6-carboxylic acid; Fluorinated spirocyclic carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1,4-Dioxaspiro[4.4]Nonane-6-Carboxylicacid,6-Fluoro-,(-)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All materials are subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric excess determination. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.