Description

Piperidine, 2-(Trimethylsilyl)- (9Ci) is a specialized organosilicon compound featuring a piperidine ring substituted with a trimethylsilyl group at the 2-position. This unique structure makes it a valuable silylating agent and versatile building block in advanced organic synthesis, particularly for introducing steric bulk and modifying reactivity. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those requiring silyl-protected amine functionalities.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides where the silylated piperidine moiety can impart specific biological activity.
• Organometallic Catalyst Ligand: Serves as a precursor or ligand in the development of catalysts for asymmetric synthesis and other specialized chemical transformations.
• Material Science Research: Employed in the creation of novel silicon-containing polymers or hybrid materials with tailored properties.
• Silylating Agent: Used to protect reactive amine groups during multi-step synthetic sequences, improving selectivity and yield.
• Academic & Industrial R&D: A valuable reagent for methodological studies and the exploration of new synthetic pathways in organic chemistry.

Basic Information

Item	Details
Product Name	Piperidine, 2-(Trimethylsilyl)- (9Ci)
CAS No.	174363-71-4
Molecular Formula	C8H19NSi
Molecular Weight	157.33 g/mol
Synonyms	2-(Trimethylsilyl)piperidine; 2-Trimethylsilylpiperidine; N-Trimethylsilyl-2-piperidine; 1-(Trimethylsilyl)-2-piperidine; 2-Piperidyltrimethylsilane; TMS-Piperidine; (Piperidin-2-yl)trimethylsilane; 2-Trimethylsilyl-piperidine
EINECS	Contact for details

Quality Control

Every batch of Piperidine, 2-(Trimethylsilyl)- (9Ci) is produced and tested under strict quality management protocols. We ensure high purity and batch-to-batch consistency through comprehensive analytical techniques including GC, HPLC, and NMR. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.